Human Siglec-6/CD327 Protein (SIG-HM206)
Human Siglec-6/CD327 Protein (SIG-HM206)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: >95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human Siglec-6, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 12.9ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Gln27-Val331
Catalog #SIG-HM206
Regular price $240.00
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Product Description

Recombinant Human Siglec-6/CD327 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Gln27-Val331.

Product Background

Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Product Category

Recombinant Protein

Protein

Siglec-6/CD327

Synonyms

CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec-6; SIGLEC6; CD33L; OBBP1

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gln27-Val331

Molecular Weight

The protein has a predicted MW of 60.5 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human Siglec-6, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 12.9ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

>95% as determined by Bis-Tris PAGE

Endotoxin

Less than 0.1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Siglec-6, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 12.9ng/ml determined by ELISA (QC Test). Immobilized Human Siglec-6, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 12.9ng/ml determined by ELISA (QC Test).
Human Siglec-6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Siglec-6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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