Human Siglec-9 Protein (SIG-HM219)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Gln18-Gly348
Catalog #SIG-HM219
Regular price $270.00
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Product Description
Recombinant Human Siglec-9 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln18-Gly348.
Product Background
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation. Thus, when the mucin MUC1 is expressed on cancer cells, it is decorated by multiple short, sialylated O-linked glycans (MUC1-ST).
Product Category
Recombinant Protein
Target
Siglec-9
Synonyms
CD329; CDw329; FOAP-9; OBBP-Like; Siglec-9; SIGLEC9
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gln18-Gly348
Molecular Weight
The protein has a predicted MW of 62.8 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human Siglec-9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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