Product Description |
Recombinant Human SLAMF6/NTB-A Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Met226. |
Product Background |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. |
Product Category |
Recombinant Protein |
Target |
SLAMF6/NTB-A |
Synonyms |
ANK-T-B-antigen; NTB-A; CD352; SLAMF6; KALI; Ly108; NK-T-B-antigen; KALIb; SF2000 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln22-Met226 |
Molecular Weight |
The protein has a predicted MW of 26 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human SLAMF6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SLAMF6 Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Human SLAMF6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SLAMF6 Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA. |
|
|
Human SLAMF6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human SLAMF6 is greater than 95% as determined by SEC-HPLC. |
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