Product Description |
Recombinant Human SLAMF7/CRACC/CD319 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser23-Met226. |
Product Background |
CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. |
Product Category |
Recombinant Protein |
Target |
SLAMF7/CRACC/CD319 |
Synonyms |
CD2 subset 1; CRACC; Novel Ly9; CD319; SLAMF7; CS1; 19A; FOAP-12 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser23-Met226 |
Molecular Weight |
The protein has a predicted MW of 49.2 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human SLAMF7, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC50 10.4ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Human SLAMF7, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC50 10.4ng/ml determined by ELISA. |
|
|
Human SLAMF7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human SLAMF7 is greater than 95% as determined by SEC-HPLC. |
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