Human SLAMF7/CRACC/CD319 Protein (SMF-HM307)

  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human SLAMF7, mFc Tag at 0.2ug/ml (100ul/Well). Dose response curve for Anti-SLAMF7 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Ser23-Met226

Catalog: SMF-HM307

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Product Description Recombinant Human SLAMF7/CRACC/CD319 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ser23-Met226

Product Background

CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.

Product Category

Recombinant Protein

Target

SLAMF7/CRACC/CD319
Synonyms CD2 subset 1; CRACC; Novel Ly9; CD319; SLAMF7; CS1; 19A; FOAP-12

Gene/Protein ID

Q9NQ25-1

Species

Human

Exact Sequence

Ser23-Met226
Molecular Weight The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human SLAMF7, mFc Tag at 0.2ug/ml (100ul/Well). Dose response curve for Anti-SLAMF7 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-mFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human SLAMF7, mFc Tag at 0.2ug/ml (100ul/Well). Dose response curve for Anti-SLAMF7 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA.
The purity of Human SLAMF7 is greater than 95% as determined by SEC-HPLC.
Human SLAMF7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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