Human SLC39A8 Protein (SLC-HM1A8)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human SLC39A8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SLC39A8 Antibody, Rabbit Fc Tag with the EC50 of 3.9ng/ml determined by ELISA.
Amino Acid Range: Glu23-Gly132

Catalog #SLC-HM1A8

Price

$1,300.00

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Human SLC39A8 Protein (SLC-HM1A8) Summary

Product Description	Recombinant Human SLC39A8 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu23-Gly132.
Product Background	The Zn transporter ZIP8 (also known as SLC39A8) is an important Zn2+ importer; aberrant Zn2+ influx mediated by ZIP8 can lead to the pathogenesis of osteoarthritis and inflammatory diseases. ZIP8 also mediates the cellular uptake of divalent metal ions including iron, manganese, and the toxic heavy metal cadmium.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins

Protein	SLC39A8
Synonyms	LZT-Hs6; ZIP-8; BIGM103; ZIP8; PP3105
Accession	Q9C0K1-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu23-Gly132
Molecular Weight	The protein has a predicted MW of 13.28 kDa. Due to glycosylation, the protein migrates to 27-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human SLC39A8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SLC39A8 Antibody, Rabbit Fc Tag with the EC50 of 3.9ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS, 8% trehalose (pH 7.4).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human SLC39A8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SLC39A8 Antibody, Rabbit Fc Tag with the EC50 of 3.9ng/ml determined by ELISA.
	Human SLC39A8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human SLC39A8 is greater than 95% as determined by SEC-HPLC.

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