Name: Human Soluble IL-6 R alpha/CD126 Protein (ILR-HM126)
Brand: KactusBio
SKU: ILR-HM126-100UG
Price: 379.5 USD
Availability: InStock

Human Soluble IL-6 R alpha/CD126 Protein (ILR-HM126)

Immobilized Human IL-6, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human Soluble IL-6 R alpha, His Tag with the EC50 of 99.2ng/ml determined by ELISA (QC Test).

Human Soluble IL-6 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human Soluble IL-6 R alpha is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Human IL-6, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human Soluble IL-6 R alpha, His Tag with the EC50 of 99.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Leu20-Pro355

Catalog #ILR-HM126

Size

100UG

500UG

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Product Description	Recombinant Human Soluble IL-6 R alpha/CD126 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu20-Pro355.
Product Background	The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
Product Category	Recombinant Protein / Antibody discovery

Protein	Soluble IL-6 R alpha/CD126
Synonyms	sIL6R; Soluble IL-6 R alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; IL6R; CD126; IL6RQ; gp80
Accession	P08887-2
Species	Human
Biotinylated	no
Amino Acid Range	Leu20-Pro355
Molecular Weight	The protein has a predicted MW of 39.14 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-6, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human Soluble IL-6 R alpha, His Tag with the EC50 of 99.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 0.1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-6, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human Soluble IL-6 R alpha, His Tag with the EC50 of 99.2ng/ml determined by ELISA (QC Test).
	Human Soluble IL-6 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Soluble IL-6 R alpha is greater than 95% as determined by SEC-HPLC.