Human SOST/Sclerostin Protein (SOT-HM101)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human SOST, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.6ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln24-Tyr213
Catalog #SOT-HM101
Regular price $330.00
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Product Description

Recombinant Human SOST/Sclerostin Protein is expressed from HEK293 with His tag at the N-terminus.It contains Gln24-Tyr213.

Product Background

SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

SOST/Sclerostin

Synonyms

sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gln24-Tyr213

Molecular Weight

The protein has a predicted MW of 22.61 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human SOST, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

N-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human SOST, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.6ng/ml determined by ELISA. Immobilized Human SOST, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.6ng/ml determined by ELISA.
Human SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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