Product Description |
Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser2-Thr166. |
Product Background |
Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells. |
Product Category |
Recombinant Protein |
Target |
TACI/TNFRSF13B |
Synonyms |
CD267; TNFRSF13B; TACI; CVID; CVID2; IGAD2; RYZN; TACI |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser2-Thr166 |
Molecular Weight |
The protein has a predicted MW of 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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|
Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). |
|
|
Human TACI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human TACI is greater than 95% as determined by SEC-HPLC. |
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