Human TACI/TNFRSF13B Protein (TAC-HM213)
Human TACI/TNFRSF13B Protein (TAC-HM213)
Human TACI/TNFRSF13B Protein (TAC-HM213)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser2-Thr166
Catalog #TAC-HM213
Regular price $297.00
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Product Description

Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser2-Thr166.

Product Background

Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
TACI/TNFRSF13B
Synonyms
CD267; TNFRSF13B; TACI; CVID; CVID2; IGAD2; RYZN; TACI
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ser2-Thr166
Molecular Weight
The protein has a predicted MW of 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).
Human TACI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TACI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Loaded Human TACI, hFc Tag on ProA-Biosensor can bind Human APRIL (Trimer), His-Flag Tag with an affinity constant of 0.76nM as determined in BLI assay (Gator® Prime). Loaded Human TACI, hFc Tag on ProA-Biosensor can bind Human APRIL (Trimer), His-Flag Tag with an affinity constant of 0.76nM as determined in BLI assay (Gator® Prime).
The purity of Human TACI is greater than 95% as determined by SEC-HPLC. The purity of Human TACI is greater than 95% as determined by SEC-HPLC.
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