Name: Human TACI/TNFRSF13B Protein (TAC-HM213)
Brand: KactusBio
SKU: TAC-HM213-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).
Amino Acid Range: Ser2-Thr166

Catalog #TAC-HM213

Size

100UG

500UG

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Human TACI/TNFRSF13B Protein (TAC-HM213) Summary

Product Description	Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser2-Thr166.
Product Background	Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human TACI/TNFRSF13B Protein (TAC-HM213) Specifications/Details

Protein	TACI/TNFRSF13B
Synonyms	CD267; TNFRSF13B; TACI; CVID; CVID2; IGAD2; RYZN; TACI
Accession	O14836-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser2-Thr166
Molecular Weight	The protein has a predicted MW of 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human BAFF Trimer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).
	Human TACI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human TACI, hFc Tag on ProA-Biosensor can bind Human APRIL (Trimer), His-Flag Tag with an affinity constant of 0.76nM as determined in BLI assay (Gator® Prime).
	Loaded Human TACI, hFc Tag on ProA-Biosensor can bind Human BAFF (Trimer), His-Flag Tag with an affinity constant of 1.53 nM as determined in BLI assay (Gator® Prime).
	The purity of Human TACI is greater than 95% as determined by SEC-HPLC.