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Human TACI/TNFRSF13B Protein, Ultra Low Endotoxin (TAC-HM213-UL) Summary
Product Description |
Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser2-Thr166. |
Product Background |
Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human TACI/TNFRSF13B Protein, Ultra Low Endotoxin (TAC-HM213-UL) Specifications/Details
Protein |
TACI/TNFRSF13B |
Synonyms |
CD267; TNFRSF13B; TACI; CVID; CVID2; IGAD2; RYZN; TACI |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser2-Thr166 |
Molecular Weight |
The protein has a predicted MW of 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human BAFF Trimer, His Tag (Cat. BAF-HM112) at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Human BAFF Trimer, His Tag (Cat. BAF-HM112) at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). |
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Immobilized Biotinylated Human APRIL (Trimer), His Avi Tag (Cat. APR-HM410B) at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human TACI, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA. |
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Human TACI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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Loaded Human TACI, hFc Tag on ProA-Biosensor can bind Human APRIL (Trimer), His-Flag Tag (Cat. APR-HM110) with an affinity constant of 0.76nM as determined in BLI assay . |
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Loaded Human TACI, hFc Tag on ProA-Biosensor can bind Human BAFF (Trimer), His-Flag Tag (Cat. BAF-HM112) with an affinity constant of 1.53 nM as determined in BLI assay . |
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The purity of Human TACI is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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