Product Description |
Recombinant Human TFF1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu25-Phe84. |
Product Background |
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. |
Product Category |
Recombinant Protein |
Target |
TFF1 |
Synonyms |
Trefoil factor 1; Bcei; BCEI; D21S21; HP1.A; HPS2; pNR-2; Polypeptide P1.A; PS2; TFF1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu25-Phe84 |
Molecular Weight |
The protein has a predicted MW of 33.3 kDa. Due to glycosylation, the protein migrates to 40-45 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human TFF1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human TFF1 is greater than 95% as determined by SEC-HPLC. |
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