Human TFPI Protein (TFP-HM401)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asp29-Lys282

Catalog: TFP-HM401

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Product Description Recombinant Human TFPI Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp29-Lys282.

Product Background

Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.

Product Category

Recombinant Protein

Target

TFPI
Synonyms LACI; TFPI1; EPI; TFI; convertin; TFPI
Accession

Species

Human

Amino Acid Range

Asp29-Lys282
Molecular Weight The protein has a predicted MW of 32.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Product Tag

C-His-Avi

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, the IC50 value is < 0.75 nM.
The purity of Human TFPI is greater than 95% as determined by SEC-HPLC.
Human TFPI on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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