• Express System: HEK293
  • Product Tag: C-mFc-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human TGF-beta RII, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test).
  • Amino Acid Range: Ile24-Asp159
Catalog #TGF-HM3R2
Price
Regular price $297.00
Regular price Sale price $297.00
/
Size
Avantor VWR Fisher Scientific

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Non-biotinylated Human TGF-beta RII/TGFBR2 Protein (TGF-HM3R2) Summary

Product Description

 Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at C-Terminus.It contains Ile24-Asp159.

Product Background

 The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.

Non-biotinylated Human TGF-beta RII/TGFBR2 Protein (TGF-HM3R2) Specifications/Details

Protein
 TGF-beta RII/TGFBR2
Synonyms
 TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II;TGF beta R2; TbR-II; T beta R-II
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ile24-Asp159
Molecular Weight
 The protein has a predicted MW of 44 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human TGF-beta RII, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test).
Product Tag
 C-mFc-Avi
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human TGF-beta RII, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test). Immobilized Human TGF-beta RII, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test).
Immobilized Human Mature TGF beta 1, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TGF-beta RII, mFc Tag with the EC50 of 3.8ng/ml determined by ELISA. Immobilized Human Mature TGF beta 1, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TGF-beta RII, mFc Tag with the EC50 of 3.8ng/ml determined by ELISA.
Human TGF-beta RII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TGF-beta RII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TGF-beta RII is greater than 95% as determined by SEC-HPLC. The purity of Human TGF-beta RII is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...