• Express System: HEK293
  • Product Tag: C-mFc-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu34-Glu125
Catalog #TGF-HM6R1
Price
Regular price $32230
Regular price Sale price $32230
/
Size
Avantor VWR Fisher Scientific

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Non-biotinylated Human TGFBR1 Protein (TGF-HM6R1) Summary

Product Description

 Recombinant Human TGFBR1 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus.It contains Leu34-Glu125.

Product Background

 transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.

Non-biotinylated Human TGFBR1 Protein (TGF-HM6R1) Specifications/Details

Protein
 TGFBR1
Synonyms
 AAT5; ACVRLK4; ALK-5; ALK5; LDS1A; LDS2A; SKR4; tbetaR-I; TGFB1R1; TGF-beta RI; TGFbetaRI; TGFBR1; TGF-bRI; TGFR-1; tβR-I; TGF-β RI; TGFβRI;TGFR1;tbR-I; t beta R-I; TGF-b RI; TGFbRI; TGF beta RI
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Leu34-Glu125
Molecular Weight
 The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result.
Product Tag
 C-mFc-Avi
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human TGFBR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TGFBR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC. The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...