Human TGFBR1 Protein (TGF-HM6R1)
Human TGFBR1 Protein (TGF-HM6R1)
  • Express System: HEK293
  • Product Tag: C-mFc-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.35 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Leu34-Glu125
Catalog #TGF-HM6R1
Regular price $293.00
/
Size

Order now, ships by:

Product Description

Recombinant Human TGFBR1 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus.It contains Leu34-Glu125.

Product Background

transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.

Product Category

Recombinant Protein / Antibody discovery

Protein

TGFBR1

Synonyms

AAT5; ACVRLK4; ALK-5; ALK5; LDS1A; LDS2A; SKR4; tbetaR-I; TGFB1R1; TGF-beta RI; TGFbetaRI; TGFBR1; TGF-bRI; TGFR-1; tβR-I; TGF-β RI; TGFβRI

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Leu34-Glu125

Molecular Weight

The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 0.35 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-mFc-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TGFBR1, mFc Tag captured on CM5 Chip via Protein A can bind Human Mature TGF beta 1, No Tag with an affinity constant of 0.35 uM as determined in SPR assay (Biacore T200). Human TGFBR1, mFc Tag captured on CM5 Chip via Protein A can bind Human Mature TGF beta 1, No Tag with an affinity constant of 0.35 uM as determined in SPR assay (Biacore T200).
Human TGFBR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TGFBR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC. The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed