Product Description |
Recombinant Human TGM2 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ala2-Ala687. |
Product Background |
Transglutaminase 2 (TGM2) is a member of the transglutaminase family, and it is reported to be associated with chemoresistance in various types of cancer. TGM2 was demonstrated to affect the chemosensitivity of osteosarcoma cells via regulation of the activation of mitogen‑activated protein kinase and AKT serine/threonine kinase pathways. |
Product Category |
Recombinant Protein |
Target |
TGM2 |
Synonyms |
Heart G alpha(h); TGM2; tTG; tTgase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase II; Transglutaminase-2; TG2; G-ALPHA-h; GNAH; HEL-S-45; C polypeptide; TGase-2; TGase-H; TGCGNAH |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala2-Ala687 |
Molecular Weight |
The protein has a predicted MW of 78.4 kDa same as Bis-Tris PAGE result. |
Activity |
Immobilized Human TGM2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-TGM2 Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-His |
Express System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Human TGM2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-TGM2 Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA. |
|
|
Human TGM2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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