Human TGM2 Protein (TGM-HE102)

Express System: E.coli
Product Tag: N-His
Purity: > 95% as determined by Tris-Bis PAGE
Activity: Immobilized Human TGM2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TGM2 Antibody, hFc Tag with the EC50 of 9.3ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ala2-Ala687

Catalog: TGM-HE102

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Product Description	Recombinant Human TGM2 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ala2-Ala687.
Product Background	Transglutaminase 2 (TGM2) is a member of the transglutaminase family, and it is reported to be associated with chemoresistance in various types of cancer. TGM2 was demonstrated to affect the chemosensitivity of osteosarcoma cells via regulation of the activation of mitogen‑activated protein kinase and AKT serine/threonine kinase pathways.
Product Category	Recombinant Protein

Target	TGM2
Synonyms	Heart G alpha(h); TGM2; tTG; tTgase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase II; Transglutaminase-2; TG2; G-ALPHA-h; GNAH; HEL-S-45; C polypeptide; TGase-2; TGase-H; TGCGNAH
Gene/Protein ID	P21980-1
Species	Human
Exact Sequence	Ala2-Ala687
Molecular Weight	The protein has a predicted MW of 78.4 kDa same as Tris-Bis PAGE result.
Activity	Immobilized Human TGM2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TGM2 Antibody, hFc Tag with the EC50 of 9.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Express System	E.coli
Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human TGM2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TGM2 Antibody, hFc Tag with the EC50 of 9.3ng/ml determined by ELISA.
	Human TGM2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.