Name: Human TIMP-2 Protein (TIM-HM1P2)
Brand: KactusBio
SKU: TIM-HM1P2-100UG
Price: 264.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Human TIMP-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TIMP-2 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Cys27-Pro220

Catalog #TIM-HM1P2

Size

100UG

500UG

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Product Description	Recombinant Human TIMP-2 Protein Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Pro220.
Product Background	Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs).TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities.
Product Category	Recombinant Protein / Antibody discovery

Protein	TIMP-2
Synonyms	CSC-21K; TIMP2; DDC8; TIMP-2
Accession	P16035
Species	Human
Biotinylated	no
Amino Acid Range	Cys27-Pro220
Molecular Weight	The protein has a predicted MW of 22.9 kDa. Due to glycosylation, the protein migrates to 24-26 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Human TIMP-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TIMP-2 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Human TIMP-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TIMP-2 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test).
	Human TIMP-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TIMP-2 is greater than 95% as determined by SEC-HPLC.