Product Description |
Recombinant Human TIMP1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Cys24-Ala207. |
Product Background |
Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner. |
Product Category |
Recombinant Protein |
Target |
TIMP1 |
Synonyms |
Metalloproteinase inhibitor 1; Collagenase inhibitor 16C8 fibroblast; Erythroid-potentiating activity; CLGI; EPA; EPATIMP-1; EPO; TPA-S1; TPAS1; TPA-induced protein; Tissue inhibitor of metalloproteinases 1; TIMP-1; TIMP |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Cys24-Ala207 |
Molecular Weight |
The protein has a predicted MW of 47.01 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human TIMP1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human TIMP1 is greater than 95% as determined by SEC-HPLC. |
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