Human TIMP1 Protein (TIM-HM201)
Catalog: TIM-HM201
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| Product Description | Recombinant Human TIMP1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Cys24-Ala207. |
Product Background |
Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner. |
Product Category |
Recombinant Protein |
Target |
TIMP1 |
| Synonyms | Metalloproteinase inhibitor 1; Collagenase inhibitor 16C8 fibroblast; Erythroid-potentiating activity; CLGI; EPA; EPATIMP-1; EPO; TPA-S1; TPAS1; TPA-induced protein; Tissue inhibitor of metalloproteinases 1; TIMP-1; TIMP |
Gene/Protein ID |
NP_003245.1 |
Species |
Human |
Exact Sequence |
Cys24-Ala207 |
| Molecular Weight | The protein has a predicted MW of 47.01 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human TIMP1 is greater than 95% as determined by SEC-HPLC. |
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Human TIMP1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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