Human TNFR1/CD120a/TNFRSF1A Protein (TNF-HM1R1)
Human TNFR1/CD120a/TNFRSF1A Protein (TNF-HM1R1)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human TNFR1, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Biotinylated Human TNF alpha, His Tag with the EC50 of 16.5ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu30-Thr211
Catalog #TNF-HM1R1
Regular price $218.00
/
Size

Order now, ships by:

Product Description

Recombinant Human TNFR1/CD120a/TNFRSF1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu30-Thr211.

Product Background

Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling.

Product Category

Recombinant Protein / Antibody discovery

Protein

TNFR1/CD120a/TNFRSF1A

Synonyms

TNF-R1; TNF-RI; TNFR-I; TNFR1; CD120a; TNFRSF1A; FPF; TBP1; TNF-R; TNF-R55; TNFAR; TNFR60; p55; p60; MS5; p55-R; TNF-R-I; TNFR1-d2

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Leu30-Thr211

Molecular Weight

The protein has a predicted MW of 23.3 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human TNFR1, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Biotinylated Human TNF alpha, His Tag with the EC50 of 16.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human TNFR1, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Biotinylated Human TNF alpha, His Tag with the EC50 of 16.5ng/ml determined by ELISA. Immobilized Human TNFR1, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Biotinylated Human TNF alpha, His Tag with the EC50 of 16.5ng/ml determined by ELISA.
Human TNFR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TNFR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TNFR1 is greater than 95% as determined by SEC-HPLC. The purity of Human TNFR1 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed