Name: Human TNFR1/CD120a/TNFRSF1A Protein (TNF-HM2R1)
Brand: KactusBio
SKU: TNF-HM2R1-100UG
Price: 240.0 USD
Availability: InStock

Human TNFR1/CD120a/TNFRSF1A Protein (TNF-HM2R1)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human TNFR1, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Leu30-Thr211

Catalog #TNF-HM2R1

Size

100UG

500UG

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Product Description	Recombinant Human TNFR1/CD120a/TNFRSF1A Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu30-Thr211.
Product Background	Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling.
Product Category	Recombinant Protein

Target	TNFR1/CD120a/TNFRSF1A
Synonyms	TNF-R1; TNF-RI; TNFR-I; TNFR1; CD120a; TNFRSF1A; FPF; TBP1; TNF-R; TNF-R55; TNFAR; TNFR60; p55; p60; MS5; p55-R; TNF-R-I; TNFR1-d2
Accession	P19438-1
Species	Human
Biotinylated	no
Amino Acid Range	Leu30-Thr211
Molecular Weight	The protein has a predicted MW of 48 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human TNFR1, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human TNFR1, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA.
	Human TNFR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TNFR1 is greater than 95% as determined by SEC-HPLC.

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