Name: Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2)
Brand: KactusBio
SKU: TNF-HM2R2-100UG
Price: 240.0 USD
Availability: InStock

Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2)

Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TNFR2, hFc Tag with the EC50 of 8.5ng/ml determined by ELISA (QC Test).

Immobilized Human TNFR2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-TNFR2 Antibody, hFc Tag with the EC50 of 19ng/ml determined by ELISA.

Human TNFR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human TNFR2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TNFR2, hFc Tag with the EC50 of 8.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Leu23-Asp257

Catalog #TNF-HM2R2

Size

100UG

500UG

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Product Description	Recombinant Human TNFR2/CD120b/TNFRSF1B Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Asp257.
Product Background	Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Product Category	Recombinant Protein

Protein	TNFR2/CD120b/TNFRSF1B
Synonyms	CD120b; Etanercept; p75TBPII; p75TNFR; TNF RII; TNF-R2; TNF-R75; TNFR80; TNFRSF1B; TNFR2; TBPII; TNFBR; TNFR1B
Accession	P20333-1
Species	Human
Biotinylated	no
Amino Acid Range	Leu23-Asp257
Molecular Weight	The protein has a predicted MW of 51.89 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TNFR2, hFc Tag with the EC50 of 8.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human TNF alpha, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TNFR2, hFc Tag with the EC50 of 8.5ng/ml determined by ELISA (QC Test).
	Immobilized Human TNFR2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-TNFR2 Antibody, hFc Tag with the EC50 of 19ng/ml determined by ELISA.
	Human TNFR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TNFR2 is greater than 95% as determined by SEC-HPLC.