Product Description |
Recombinant Human TNFSF15 (R32A, R85A) Trimer Protein is expressed from HEK293 with His tag and Flag tag at the N-terminus.It contains Asp91-Leu251 trimer design. |
Product Background |
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
TNFSF15 |
Synonyms |
TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asp91-Leu251 |
Molecular Weight |
The protein has a predicted MW of 58.15 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-His-Flag |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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