Human TPM1-Protein (TPM-HE101)
Human TPM1-Protein (TPM-HE101)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Met1-Met284
Catalog #TPM-HE101
Regular price $330.00
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Human TPM1-Protein (TPM-HE101) Summary

Product Description

Recombinant Human TPM1-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284.

Product Background

Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human TPM1-Protein (TPM-HE101) Specifications/Details

Protein
TPM1
Synonyms
C15orf13; TMSA; CMD1Y; CMH3; HTM-alpha; LVNC9
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Met284
Molecular Weight
The protein has a predicted MW of 34.26 kDa same as Bis-Tris PAGE result.

Product Tag

N-His
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS, 150mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TPM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TPM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TPM1 is greater than 90% as determined by SEC-HPLC. The purity of Human TPM1 is greater than 90% as determined by SEC-HPLC.
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