Name: Human TPM1-Protein (TPM-HE101)
Brand: KactusBio
SKU: TPM-HE101-100UG
Price: 330.0 USD
Availability: InStock

Catalog #TPM-HE101

Size

100UG

500UG

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Human TPM1-Protein (TPM-HE101) Summary

Product Description	Recombinant Human TPM1-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284.
Product Background	Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human TPM1-Protein (TPM-HE101) Specifications/Details

Protein	TPM1
Synonyms	C15orf13; TMSA; CMD1Y; CMH3; HTM-alpha; LVNC9
Accession	NP_000357.3
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Met284
Molecular Weight	The protein has a predicted MW of 34.26 kDa same as Bis-Tris PAGE result.
Product Tag	N-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS, 150mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human TPM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TPM1 is greater than 90% as determined by SEC-HPLC.