Human TPM1-Protein (TPM-HE101)
Human TPM1-Protein (TPM-HE101)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Met1-Met284
Catalog #TPM-HE101
Regular price $300.00
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Product Description
Recombinant Human TPM1-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284.
Product Background
Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future.
Product Category
Recombinant Protein
Target
TPM1
Synonyms
C15orf13; TMSA; CMD1Y; CMH3; HTM-alpha; LVNC9
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Met284
Molecular Weight
The protein has a predicted MW of 34.26 kDa same as Bis-Tris PAGE result.
Product Tag
N-His
Express System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS, 150mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human TPM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TPM1 is greater than 90% as determined by SEC-HPLC.

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