Human TPM1-Protein (TPM-HE101)

  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Met1-Met284

Catalog: TPM-HE101

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Product Description Recombinant Human TPM1-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284.

Product Background

 Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future.

Product Category

 Recombinant Protein

Target

 TPM1
Accession

Species

 Human

Amino Acid Range

 Met1-Met284
Molecular Weight The protein has a predicted MW of 34.26 kDa same as Tris-Bis PAGE result.

Product Tag

 N-His

Express System

 E.coli
Purity > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS, 150mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human TPM1 is greater than 90% as determined by SEC-HPLC.
Human TPM1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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