Human TPM1-Protein (TPM-HE101) Summary
Product Description |
Recombinant Human TPM1-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284. |
Product Background |
Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human TPM1-Protein (TPM-HE101) Specifications/Details
Protein |
TPM1 |
Synonyms |
C15orf13; TMSA; CMD1Y; CMH3; HTM-alpha; LVNC9 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Met284 |
Molecular Weight |
The protein has a predicted MW of 34.26 kDa same as Bis-Tris PAGE result. |
Product Tag |
N-His |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS, 150mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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