Name: Human Thyroid Peroxidase Protein (TPO-HM101)
Brand: KactusBio
SKU: TPO-HM101-100UG
Price: 300.0 USD
Availability: InStock

Human Thyroid Peroxidase Protein (TPO-HM101)

Human Thyroid Peroxidase on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human Thyroid Peroxidase is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Phe19-Arg846

Catalog #TPO-HM101

Size

100UG

500UG

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Product Description	Recombinant Human Thyroid Peroxidase Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe19-Arg846.
Product Background	Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune thyroid disease, for example, the expression of thyroid peroxidase is lost in papillary thyroid carcinoma.
Product Category	Recombinant Protein / Antibody discovery

Protein	Thyroid Peroxidase
Synonyms	Thyroid peroxidase; TPO
Accession	P07202-1
Species	Human
Biotinylated	no
Amino Acid Range	Phe19-Arg846
Molecular Weight	The protein has a predicted MW of 90.6 kDa. Due to glycosylation, the protein migrates to 95-105 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human Thyroid Peroxidase on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Thyroid Peroxidase is greater than 95% as determined by SEC-HPLC.