Name: Non-biotinylated Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM4R1)
Brand: KactusBio
SKU: TRL-HM4R1-100UG
Price: 239.8 USD
Availability: InStock

Non-biotinylated Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM4R1)

Human TRAIL R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human TRAIL, No Tag-with an affinity constant of 1.02 nM as determined in SPR assay (Biacore T200).

Human TRAIL R1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

The purity of Human TRAIL R1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 1.02 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Pro34-Asn239

Catalog #TRL-HM4R1

Size

100UG

500UG

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Non-biotinylated Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM4R1) Summary

Product Description	Recombinant Human TRAIL R1/DR4/TNFRSF10A Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Pro34-Asn239.
Product Background	Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The expression of apoptosis-inducing TRAIL-R1 and TRAIL-R2 and of the decoy receptors TRAIL-R3 and TRAIL-R4 was systematically studied in all developmental stages of peripheral B cells isolated from the blood and secondary lymphoid organs. Expression of TRAIL-Rs is modulated along development, with highest levels observed in germinal center B cells.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Non-biotinylated Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM4R1) Specifications/Details

Protein	TRAIL R1/DR4/TNFRSF10A
Synonyms	DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Accession	O00220
Species	Human
Biotinylated	no
Amino Acid Range	Pro34-Asn239
Molecular Weight	The protein has a predicted MW of 24.7 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 1.02 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human TRAIL R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human TRAIL, No Tag-with an affinity constant of 1.02 nM as determined in SPR assay (Biacore T200).
	Human TRAIL R1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Human TRAIL R1 is greater than 95% as determined by SEC-HPLC.