Product Description |
Recombinant Human Transthyretin/Prealbumin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly21-Glu147. |
Product Background |
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue. |
Product Category |
Recombinant Protein |
Target |
Transthyretin/Prealbumin |
Synonyms |
Transthyretin; ATTR; Prealbumin; TBPA; TTR; PALB; CTS; CTS1; HsT2651; HEL111 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly21-Glu147 |
Molecular Weight |
The protein has a predicted MW of 14.9 kDa. Due to glycosylation, the protein migrates to 16 kDa and 39 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human Transthyretin/Prealbumin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human Transthyretin/Prealbumin is greater than 95% as determined by SEC-HPLC. |
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