Product Description |
Recombinant Human TrkA-Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala33-Gly417. |
Product Background |
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects. |
Product Category |
Recombinant Protein |
Target |
TrkA |
Synonyms |
Trk-A; NTRK1; MTC; TRK; TRKA; TrkA-I; TrkA I; TrkAI |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala33-Gly417 |
Molecular Weight |
The protein has a predicted MW of 43.00 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human TrkA-on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human TrkA is greater than 95% as determined by SEC-HPLC. |
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