Name: Human TrkB/NTRK2 Protein (TKB-HM101)
Brand: KactusBio
SKU: TKB-HM101-100UG
Price: 247.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human/Murine/Rat BDNF, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TrkB, His Tag with the EC50 of 0.39ug/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Cys32-His430

Catalog #TKB-HM101

Size

100UG

500UG

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Human TrkB/NTRK2 Protein (TKB-HM101) Summary

Product Description	Recombinant Human TrkB/NTRK2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys32-His430.
Product Background	Neuron differentiation is likely regulated by a combination of transcription and growth factors. Embryonically, most geniculate neuron development is regulated by the growth factor brain derived neurotrophic factor (BDNF). BDNF expression becomes restricted to subpopulations of taste receptor cells with specific functions,the receptor for BDNF, tropomyosin kinase B receptor (TrkB), may also become developmentally restricted to a subset of taste neurons and could be one factor that is differentially expressed across taste neuron subsets.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human TrkB/NTRK2 Protein (TKB-HM101) Specifications/Details

Protein	TrkB/NTRK2
Synonyms	GP145-TrkB; NTRK2; TRKB
Accession	AAH31835
Species	Human
Biotinylated	no
Amino Acid Range	Cys32-His430
Molecular Weight	The protein has a predicted MW of 45.2 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human/Murine/Rat BDNF, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TrkB, His Tag with the EC50 of 0.39ug/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human/Murine/Rat BDNF, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TrkB, His Tag with the EC50 of 0.39ug/ml determined by ELISA (QC Test).
	Human TrkB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TrkB is greater than 95% as determined by SEC-HPLC.