Human TSLPR Protein (TSP-HM10R)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human TSLPR, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Exact Sequence: Gly25-Lys231

Catalog: TSP-HM10R

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Product Description Recombinant Human TSLPR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly25-Lys231.

Product Background

TSLP is an epithelial cell-derived cytokine synthesized in response to various stimuli, including protease allergens and microorganisms like viruses and bacteria. Biological functions of TSLP require heterodimer formation between the TSLP receptor (TSLPR) and IL-7 receptor-α, which polarize dendritic cells to induce type 2 inflammation and directly expand and/or activate Th2 cells, group 2 innate lymphoid cells, basophils, and other immune cells.

Product Category

Recombinant Protein

Target

TSLPR
Synonyms TSLP receptor; TSLPR; CRL2; CRLF2Y; CRLF2; IL-XR; p2RY8/CRLF2 fusion; CRLF2

Gene/Protein ID

Q9HC73-1

Species

Human

Exact Sequence

Gly25-Lys231
Molecular Weight The protein has a predicted MW of 25.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human TSLPR, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human TSLPR, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA (QC Test).
Immobilized Human TSLP, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 1.33ug/ml determined by ELISA.
The purity of Human TSLPR is greater than 95% as determined by SEC-HPLC.
Human TSLPR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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