Name: Human TSLPR Protein (TSP-HM10R)
Brand: KactusBio
SKU: TSP-HM10R-100UG
Price: 300.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human TSLP, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 0.32ug/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gly25-Lys231

Catalog #TSP-HM10R

Size

100UG

500UG

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Product Description	Recombinant Human TSLPR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly25-Lys231.
Product Background	TSLP is an epithelial cell-derived cytokine synthesized in response to various stimuli, including protease allergens and microorganisms like viruses and bacteria. Biological functions of TSLP require heterodimer formation between the TSLP receptor (TSLPR) and IL-7 receptor-α, which polarize dendritic cells to induce type 2 inflammation and directly expand and/or activate Th2 cells, group 2 innate lymphoid cells, basophils, and other immune cells.
Product Category	Recombinant Protein / Antibody discovery

Protein	TSLPR
Synonyms	TSLP receptor; TSLPR; CRL2; CRLF2Y; CRLF2; IL-XR; p2RY8/CRLF2 fusion; CRLF2
Accession	Q9HC73-1
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Lys231
Molecular Weight	The protein has a predicted MW of 25.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human TSLP, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 0.32ug/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human TSLP, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 0.32ug/ml determined by ELISA (QC Test).
	Immobilized Human TSLPR, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA.
	Human TSLPR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TSLPR is greater than 95% as determined by SEC-HPLC.