Human ULBP-1 Protein (ULB-HM4P1)
Human ULBP-1 Protein (ULB-HM4P1)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: Immobilized Human ULBP-1, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22 ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gly26-Pro215
Catalog #ULB-HM4P1
Regular price $315.00
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Product Description

Recombinant Human ULBP-1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly26-Pro215.

Product Background

ULBP-1, or UL16-binding protein 1, is a protein that plays a significant role in the immune system, particularly in the recognition and elimination of abnormal cells, such as those found in cancer. It is a ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells and certain T cells. The interaction between ULBP-1 and NKG2D can activate these immune cells, leading to the destruction of target cells.

Product Category

Recombinant Protein / Antibody discovery

Protein

ULBP-1

Synonyms

ALCAN-beta; NKG2D ligand 1; N2DL-1; NKG2DL1; MULT-1; NKG2DL; AET1I; ULBP1; ULBP-1;ALCAN-β

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gly26-Pro215

Molecular Weight

The protein has a predicted MW of 25.2 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human ULBP-1, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22 ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in 20 mM PB, 0.5 M NaCl, 0.1 M L-arginine (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human ULBP-1, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22 ug/ml determined by ELISA. Immobilized Human ULBP-1, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22 ug/ml determined by ELISA.
Human ULBP-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ULBP-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ULBP-1 is greater than 95% as determined by SEC-HPLC. The purity of Human ULBP-1 is greater than 95% as determined by SEC-HPLC.

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