Name: Human ULBP-4 Protein (ULB-HM204)
Brand: KactusBio
SKU: ULB-HM204-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: His31-Asp225

Catalog #ULB-HM204

Size

100UG

500UG

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Human ULBP-4 Protein (ULB-HM204) Summary

Product Description	Recombinant Human ULBP-4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His31-Asp225.
Product Background	UL16-binding proteins (ULBPs) are markers of cellular stress which are upregulated on the surface of virus-infected and tumor cells. ULBPs are expressed by a variety of leukemias, carcinomas, melanomas, and tumor cell lines.ULBP4 is associated with higher levels of CD8+/NKG2D+ lymphocytes infiltrating the carcinoma and is a prognosticator of improved survival.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human ULBP-4 Protein (ULB-HM204) Specifications/Details

Protein	ULBP-4
Synonyms	N2DL-4; NKG2DL4; RAE-1-like transcript 4; RAET1E; LETAL; N2DL4; ULBP4;
Accession	Q8TD07-1
Species	Human
Biotinylated	no
Amino Acid Range	His31-Asp225
Molecular Weight	The protein has a predicted MW of 49.12 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human ULBP-4, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
	Human ULBP-4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ULBP-4 is greater than 95% as determined by SEC-HPLC.