Human VCAM-1/CD106 Protein (VAM-HM206)
  • Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 90% as determined by Bis-Tris PAGE
  • Amino Acid Range: Phe25-Glu698
Catalog #VAM-HM206
Regular price $223.30
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Size
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Human VCAM-1/CD106 Protein (VAM-HM206) Summary

Product Description

Recombinant Human VCAM-1/CD106 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Phe25-Glu698.

Product Background

Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human VCAM-1/CD106 Protein (VAM-HM206) Specifications/Details

Protein
VCAM-1/CD106
Synonyms
V-CAM 1; VCAM-1; INCAM-100; CD106; DKFZp779G2333; MGC99561
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Phe25-Glu698
Molecular Weight
The protein has a predicted MW of 100.17 kDa. Due to glycosylation, the protein migrates to 105-125 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc (IgG1)

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 90% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human VCAM-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. Human VCAM-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
Other Available Proteins:
Finding available proteins...
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