Name: Human VEGF R2/KDR Protein (VGF-HM2R2)
Brand: KactusBio
SKU: VGF-HM2R2-100UG
Price: 264.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human VEGF165, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R2, hFc Tag with the EC50 of 7.8ng/ml determined by ELISA (QC Test).
Amino Acid Range: Ala20-Glu764

Catalog #VGF-HM2R2

Size

100UG

500UG

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Human VEGF R2/KDR Protein (VGF-HM2R2) Summary

Product Description	Recombinant Human VEGF R2/KDR Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ala20-Glu764.
Product Background	The vascular endothelial growth factor receptor-2 (VEGFR-2/KDR/flk-1) functions as the primary mediator of vascular endothelial growth factor activation in endothelial cells. Regulation of VEGFR-2 expression appears critical in mitogenesis, differentiation, and angiogenesis. Transcriptional regulation of the VEGFR-2 is complex and may involve multiple putative upstream regulatory elements including E boxes.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets \| ADC targets

Human VEGF R2/KDR Protein (VGF-HM2R2) Specifications/Details

Protein	VEGF R2/KDR
Synonyms	CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73
Accession	P35968-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala20-Glu764
Molecular Weight	The protein has a predicted MW of 109.21 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human VEGF165, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R2, hFc Tag with the EC50 of 7.8ng/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human VEGF165, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R2, hFc Tag with the EC50 of 7.8ng/ml determined by ELISA (QC Test).
	Immobilized Human VEGF R2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 9.7ng/ml determined by ELISA.
	Human VEGF R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human VEGF165, His-Avi Tag on Anti-His-Biosensor can bind Human VEGF R2, hFc Tag with an affinity constant of 2.34 nM as determined in BLI assay .
	The purity of Human VEGF R2 is greater than 95% as determined by SEC-HPLC.

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