- Express System: HEK293
- Product Tag: C-hFc
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Immobilized Human VEGF R2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 9.7ng/ml determined by ELISA (QC Test). See testing image for detail.
- Amino Acid Range: Ala20-Glu764
Product Description |
Recombinant Human VEGF R2/KDR Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala20-Glu764. |
Product Background |
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. |
Product Category |
Recombinant Protein |
Target |
VEGF R2/KDR |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala20-Glu764 |
Molecular Weight |
The protein has a predicted MW of 109.21 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human VEGF R2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 9.7ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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