Name: Human VEGF R3/FLT4 Protein (VGF-HM2R3)
Brand: KactusBio
SKU: VGF-HM2R3-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human VEGF-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R3, hFc Tag with the EC50 of 17.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Tyr25-Ile776

Catalog #VGF-HM2R3

Size

100UG

500UG

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Product Description	Recombinant Human VEGF R3/FLT4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr25-Ile776.
Product Background	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	VEGF R3/FLT4
Synonyms	VEGFR-3; FLT-4; LMPH1A; PCLFLT41; VEGFR3; FLT-41; PCL
Accession	P35916-1
Species	Human
Biotinylated	no
Amino Acid Range	Tyr25-Ile776
Molecular Weight	The protein has a predicted MW of 111.3 kDa. Due to glycosylation, the protein migrates to 135-155 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human VEGF-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R3, hFc Tag with the EC50 of 17.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 50mM Tris, 150mM NaCl, 100mM Glycine (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human VEGF-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R3, hFc Tag with the EC50 of 17.9ng/ml determined by ELISA (QC Test).
	Immobilized Human VEGF R3, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF-D, His Tag with the EC50 of 0.44ug/ml determined by ELISA.
	Human VEGF R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human VEGF R3 is greater than 95% as determined by SEC-HPLC.