Human VIPR2 Protein (VPR-HM302)
Catalog: VPR-HM302
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| Product Description | Recombinant Human VIPR2 Protein is expressed from HEK293 with mFc tag at the C-terminus.It contains Glu24-Val126. |
Product Background |
Effects of vasoactive intestinal peptide (VIP) on T cell migration are mediated by structurally distinct types I (VIPR1) and II (VIPR2) G protein-associated receptors. The two receptor types were proposed to transduce opposite effects on human T cells, since cytokine-induced chemotaxis of VIPR1-bearing HuT 78 human T cells, in contrast to T cells that express VIPR2, was inhibited by VIP. |
Product Category |
Recombinant Protein |
Target |
VIPR2 |
Gene/Protein ID |
P41587-1 |
Species |
Human |
Exact Sequence |
Glu24-Val126 |
| Molecular Weight | The protein has a predicted MW of 37.35 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-mFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human VIPR2 is greater than 95% as determined by SEC-HPLC. |
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Human VIPR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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