Human VLDLR Protein (VDR-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.72 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Gly28-Ser797

Catalog: VDR-HM101

$270.00
Size:

Order now get it on

Product Description Recombinant Human VLDLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly28-Ser797.

Product Background

VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk and preimplantation genetic testing are possible when the pathogenic variants in a family are known.

Product Category

Recombinant Protein

Target

VLDLR
Synonyms VLDL-R; VLDLR; RP11-320E16.1; CHRMQ1; FLJ35024; VLDLRCH

Gene/Protein ID

P98155-1

Species

Human

Exact Sequence

Gly28-Ser797
Molecular Weight The protein has a predicted MW of 85.9 kDa. Due to glycosylation, the protein migrates to 115-125 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 0.72 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human VLDLR, His Tag immobilized on CM5 Chip can bind Human PCSK9, His Tag with an affinity constant of 0.72 nM as determined in SPR assay (Biacore T200).
The purity of Human VLDLR is greater than 95% as determined by SEC-HPLC.
Human VLDLR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

You may also be interested in