Mouse ACE2/ACEH Protein (ACE-MM102)
Mouse ACE2/ACEH Protein (ACE-MM102)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH. The specific activity is >200 pmol/min/µg, as measured under the described conditions.
  • Amino Acid Range: Gln18-Thr740
Catalog #ACE-MM102
Regular price $396.00
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Size
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Mouse ACE2/ACEH Protein (ACE-MM102) Summary

Product Description

Recombinant Mouse ACE2/ACEH Protein is expressed from HEK293 with His tag at the C-terminus; It contains Gln18-Thr740.

Product Background

ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse ACE2/ACEH Protein (ACE-MM102) Specifications/Details

Protein
ACE2/ACEH
Synonyms
ACE-2; ACEH; ACE2
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Gln18-Thr740
Molecular Weight
The protein has a predicted MW of 84.57 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result.
Activity
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH. The specific activity is >200 pmol/min/µg, as measured under the described conditions.
Product Tag
C-His

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse ACE2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse ACE2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse ACE2 is greater than 95% as determined by SEC-HPLC. The purity of Mouse ACE2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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