Mouse ADAM8 Protein (ADM-MM108)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Pro17-Ser658

Catalog: ADM-MM108


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Product Description Recombinant Mouse ADAM8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro17-Ser658.

Product Background

A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer.

Product Category

Recombinant Protein


Synonyms ADAM 8; Ms2; Adam8; CD156a; MGC134985



Amino Acid Range

Molecular Weight The protein has a predicted MW of 71.7 kDa. The protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse ADAM8 is greater than 95% as determined by SEC-HPLC.
Mouse ADAM8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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