Mouse AGER Protein (RAG-MM10E)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly23-Ala340

Catalog: RAG-MM10E

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Product Description Recombinant Mouse AGER Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly23-Ala340.

Product Background

The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is expressed mainly in the lung, and involves multiple pathways (such as NFκB, Akt, p38, and MAP kinases) that initiate and perpetuate an unfavorable proinflammatory state.

Product Category

Recombinant Protein

Target

RAGE
Synonyms Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products; RAGE
Accession

Species

Mouse

Amino Acid Range

Gly23-Ala340
Molecular Weight The protein has a predicted MW of 34.85 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse AGER is greater than 95% as determined by SEC-HPLC.
Mouse AGER on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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