Product Description |
Recombinant Mouse AGER Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly23-Ala340. |
Product Background |
The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is expressed mainly in the lung, and involves multiple pathways (such as NFκB, Akt, p38, and MAP kinases) that initiate and perpetuate an unfavorable proinflammatory state. |
Product Category |
Recombinant Protein |
Target |
RAGE |
Synonyms |
Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products; RAGE |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Gly23-Ala340 |
Molecular Weight |
The protein has a predicted MW of 34.85 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse AGER on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse AGER is greater than 95% as determined by SEC-HPLC. |
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