Product Description |
Recombinant Mouse ALK Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser19-Cys692. |
Product Background |
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises. |
Product Category |
Recombinant Protein |
Target |
ALK |
Synonyms |
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ser19-Cys692 |
Molecular Weight |
The protein has a predicted MW of 101.11 kDa. Due to glycosylation, the protein migrates to 115-125 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS, 10% Glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Mouse ALK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse ALK is greater than 95% as determined by SEC-HPLC. |
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