Mouse APCDD1 Protein (APD-MM101)
Mouse APCDD1 Protein (APD-MM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu27-Thr492
Catalog #APD-MM101
Regular price $315.00
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Product Description
Recombinant Mouse APCDD1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu27-Thr492.
Product Background
Adenomatosis polyposis coli downregulated 1 (APCDD1), a negative regulator of Wnt signaling, was examined to understand detailed mechanisms underlying Wnt signaling tooth development. In situ hybridization showed that Apcdd1 was expressed in the condensed mesenchyme at the bud stage, and in the inner enamel epithelium (IEE), including enamel knot (EK) at the cap stage. APCDD1 modulates the gene expression of Wnt- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating the epithelial rearrangement in the IEE.
Product Category
Recombinant Protein
Target
APCDD1
Synonyms
Apcdd1; Drapc1; B7323; FP7019; HHS; HTS; HYPT1
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Leu27-Thr492
Molecular Weight
The protein has a predicted MW of 54.4 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse APCDD1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse APCDD1 is greater than 95% as determined by SEC-HPLC.

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