Mouse AREG Protein (AEG-MM201)

  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val100-Ala248

Catalog: AEG-MM201

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Product Description Recombinant Mouse AREG Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val100-Ala248.

Product Background

Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.

Product Category

Recombinant Protein

Target

AREG
Synonyms Amphiregulin; AR; SDGF; AREG; AREGB; CRDGF; MGC13647
Accession

Species

Mouse

Amino Acid Range

Val100-Ala248
Molecular Weight The protein has a predicted MW of 38.6 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.

Product Tag

N-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse AREG is greater than 95% as determined by SEC-HPLC.
Mouse AREG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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