Product Description |
Recombinant Mouse ASPH Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ile324-Ile741. |
Product Background |
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. |
Product Category |
Recombinant Protein |
Target |
ASPH |
Synonyms |
Aspartate beta-hydroxylase; ASP beta-hydroxylase; Asph; Bah;Aspartate β-hydroxylase; ASP β-hydroxylase |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ile324-Ile741 |
Molecular Weight |
The protein has a predicted MW of 49.4 kDa same as Bis-Tris PAGE result. |
Product Tag |
N-His |
Express System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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