Mouse B2M/beta 2-Microglobulin Protein (B2M-MM201)
Mouse B2M/beta 2-Microglobulin Protein (B2M-MM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ile21-Met119
Catalog #B2M-MM201
Regular price $210.00
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Product Description
Recombinant Mouse B2M/beta 2-Microglobulin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile21-Met119.
Product Background
The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.
Product Category
Recombinant Protein
Target
B2M/beta 2-Microglobulin
Synonyms
Beta-2-microglobulin;B2M;β-2-microglobulin
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ile21-Met119
Molecular Weight
The protein has a predicted MW of 38.4 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse B2M on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse B2M is greater than 95% as determined by SEC-HPLC.

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