Name: Mouse BACE-1 Protein (BAE-MM101)
Brand: KactusBio
SKU: BAE-MM101-100UG
Price: 264.0 USD
Availability: InStock

Catalog #BAE-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse BACE-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr22-Thr457.
Product Background	The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Aβ therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states.
Product Category	Recombinant Protein / Antibody discovery

Protein	BACE-1
Synonyms	Beta-secretase 1; ASP2; Asp 2; BACE1; BACE; FLJ90568; HSPC104; KIAA1149; Memapsin-2; BACE-1; EC 3.4.23; EC 3.4.23.46;β-secretase 1
Accession	P56818
Species	Mouse
Biotinylated	no
Amino Acid Range	Thr22-Thr457
Molecular Weight	The protein has a predicted MW of 49.49 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse BACE-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse BACE-1 is greater than 95% as determined by SEC-HPLC.