Mouse BAFFR/TNFRSF13C Protein (BAF-MM20R)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human BAFF (Trimer), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse BAFFR, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ser10-Ala71

Catalog: BAF-MM20R

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Product Description	Recombinant Mouse BAFFR/TNFRSF13C Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser10-Ala71.
Product Background	BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
Product Category	Recombinant Protein

Target	BAFFR/TNFRSF13C
Synonyms	CD268; BAFFR; BR3; TNFRSF13C; BROMIX; CVID4; prolixin
Gene/Protein ID	Q9D8D0-1
Species	Mouse
Exact Sequence	Ser10-Ala71
Molecular Weight	The protein has a predicted MW of 33.5 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human BAFF (Trimer), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse BAFFR, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human BAFF (Trimer), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse BAFFR, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.
	The purity of Mouse BAFFR is greater than 95% as determined by SEC-HPLC.
	Mouse BAFFR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.