Mouse BST2 Protein (BST-MM102)
Catalog: BST-MM102
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| Product Description | Recombinant Mouse BST2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Thr52-Ser152. |
Product Background |
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor. |
Product Category |
Recombinant Protein |
Target |
BST2 |
| Synonyms | BST-2; HM1.24 antigen; CD317; BST2; NPC-A-7; PDCA-1; TETHERIN |
Gene/Protein ID |
Q8R2Q8 |
Species |
Mouse |
Exact Sequence |
Thr52-Ser152 |
| Molecular Weight | The protein has a predicted MW of 13.2 kDa. Due to glycosylation, the protein migrates to 17-30 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Mouse BST2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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