Product Description |
Recombinant Mouse BTLA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu30-Gly176. |
Product Background |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. |
Product Category |
Recombinant Protein |
Target |
BTLA |
Synonyms |
CD272; BTLA; BTLA1; FLJ16065; MGC129743 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Glu30-Gly176 |
Molecular Weight |
The protein has a predicted MW of 17.8 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse BTLA-on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse BTLA is greater than 95% as determined by SEC-HPLC. |
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