Mouse BTLA Protein (BTL-MM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu30-Gly176

Catalog: BTL-MM101

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Product Description Recombinant Mouse BTLA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu30-Gly176.

Product Background

B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.

Product Category

Recombinant Protein

Target

BTLA
Synonyms CD272; BTLA; BTLA1; FLJ16065; MGC129743
Accession

Species

Mouse

Amino Acid Range

Glu30-Gly176
Molecular Weight The protein has a predicted MW of 17.8 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse BTLA is greater than 95% as determined by SEC-HPLC.
Mouse BTLA-on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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