• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asn7750-Pro8422
Catalog #MUC-MM126
Price
Regular price $34500
Regular price Sale price $34500
/
Size
Avantor VWR Fisher Scientific

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Mouse CA125/MUC16 Protein (MUC-MM126) Summary

Product Description

 Recombinant Mouse CA125/MUC16 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asn7750-Pro8422.

Product Background

 MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.

Mouse CA125/MUC16 Protein (MUC-MM126) Specifications/Details

Protein
 CA125/MUC16
Synonyms
 CA125; CA-125; CA125MUC-16; FLJ14303; MUC16;CA125MUC16
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Asn7750-Pro8422
Molecular Weight
 The protein has a predicted MW of 76.39 kDa. Due to glycosylation, the protein migrates to 35-45 kDa and 100-130 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS, 8% trehalose (pH 7.4).
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse CA125 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse CA125 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CA125 is greater than 95% as determined by SEC-HPLC. The purity of Mouse CA125 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...