Mouse CD117 Protein (CD1-MM117)
Mouse CD117 Protein (CD1-MM117)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 14.02 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Ser25-Pro523
Catalog #CD1-MM117
Regular price $315.00
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Product Description

Recombinant Mouse CD117 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser25-Pro523.

Product Background

The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.

Product Category

Recombinant Protein / Antibody discovery

Protein

CD117

Synonyms

SCFR; PBT; CD117; ckit; c-kit; KIT

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Ser25-Pro523

Molecular Weight

The protein has a predicted MW of 56.63 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 14.02 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse CD117, His Tag captured on CM5 Chip via anti-his antibody can bind Human SCF, No Tag with an affinity constant of 14.02 uM as determined in SPR assay (Biacore T200). Mouse CD117, His Tag captured on CM5 Chip via anti-his antibody can bind Human SCF, No Tag with an affinity constant of 14.02 uM as determined in SPR assay (Biacore T200).
Mouse CD117 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse CD117 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CD117 is greater than 95% as determined by SEC-HPLC. The purity of Mouse CD117 is greater than 95% as determined by SEC-HPLC.

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