Mouse CD155/PVR Protein (CD1-MM455)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse CD155, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Mouse TIGIT, hFc Tag with the EC50 of 0.23ug/ml determined by ELISA (QC Test). The affinity constant of 4.00 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Asp29-Leu348

Catalog: CD1-MM455

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Mouse CD155/PVR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp29-Leu348.
Product Background	CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
Product Category	Recombinant Protein

Target	CD155/PVR
Synonyms	CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946
Gene/Protein ID	Q8K094-1
Species	Mouse
Exact Sequence	Asp29-Leu348
Molecular Weight	The protein has a predicted MW of 35.9 kDa. Due to glycosylation, the protein migrates to 55-75 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Mouse CD155, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Mouse TIGIT, hFc Tag with the EC50 of 0.23ug/ml determined by ELISA (QC Test). The affinity constant of 4.00 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Mouse CD155, His Tag immobilized on CM5 Chip can bind Mouse TIGIT, His Tag with an affinity constant of 4.00 uM as determined in SPR assay (Biacore T200).
	Immobilized Mouse CD155, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Mouse TIGIT, hFc Tag with the EC50 of 0.23ug/ml determined by ELISA (QC Test).
	The purity of Mouse CD155 is greater than 95% as determined by SEC-HPLC.
	Mouse CD155 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.